ICRA 2012 Paper Abstract

Close

Paper WeB06.3

Khorami Llewellyn, Maral (Scuola Superiore Sant'Anna, Piazza Martiri della LibertÓ,Pisa (I), Dario, Paolo (Scuola Superiore Sant'Anna), Menciassi, Arianna (Scuola Superiore Sant'Anna - SSSA), Sinibaldi, Edoardo (Istituto Italiano di Tecnologia)

Magnetic Dragging of Vascular Obstructions by Means of Electrostatic and Antibody Binding

Scheduled for presentation during the Regular Session "Micro and Nano Robots II" (WeB06), Wednesday, May 16, 2012, 11:00−11:15, Meeting Room 6 (Oya'te)

2012 IEEE International Conference on Robotics and Automation, May 14-18, 2012, RiverCentre, Saint Paul, Minnesota, USA

This information is tentative and subject to change. Compiled on October 24, 2017

Keywords Micro/Nano Robots

Abstract

Exploitation of miniature robots and microrobots for endovascular therapeutics is a promising approach; besides chemical strategies (typically systemic), topical mechanical approaches exist for obstruction removal, which however produce harmful debris for blood circulation. Magnetic particles (MPs) are also studied for blood clot targeting. We investigated magnetic dragging of clots/debris by means of both electrostatic and antibody binding. We successfully produced magnetotactic blood clots in vitro and experimentally showed that they can be effectively dragged within a fluidic channel. We also exploited a magnetic force model in order to quantitatively analyze the experimental results, up to obtaining an estimate of the relative efficiency between electrostatic and antibody binding. Our study takes a first step towards more realistic in vivo investigations, in view of integration into microrobotic approaches to vascular obstructions removal.

 

 

Technical Content © IEEE Robotics & Automation Society

This site is protected by copyright and trademark laws under US and International law.
All rights reserved. © 2002-2017 PaperCept, Inc.
Page generated 2017-10-24  00:25:14 PST  Terms of use