ICRA 2012 Paper Abstract

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Paper TuB07.2

Kim, Dal Hyung (Drexel University), Kim, Paul (Drexel University), Julius, Agung (Rensselaer Polytechnic Institute), Kim, MinJun (Drexel University)

Three-Dimensional Control of Engineered Motile Cellular Microrobots

Scheduled for presentation during the Regular Session "Micro and Nano Robots I" (TuB07), Tuesday, May 15, 2012, 10:45−11:00, Meeting Room 7 (Remnicha)

2012 IEEE International Conference on Robotics and Automation, May 14-18, 2012, RiverCentre, Saint Paul, Minnesota, USA

This information is tentative and subject to change. Compiled on December 13, 2017

Keywords Micro/Nano Robots

Abstract

We demonstrate three-dimensional control with the eukaryotic cell Tetrahymena pyriformis (T. pyriformis) using two sets of Helmholtz coils for xy-plane motion and a single electromagnet for vertical motion. T. pyriformis is modified to have artificial magnetotaxis with internalized magnetite. Since the magnetic fields exerted by electromagnets are relatively uniform in the working space, the magnetite exerts only torque, without translational force, which enabled us to guide the cellís swimming direction while the swimming force is exerted only by the cellís motile organelles. A stronger magnetic force was necessary to steer cells to the z¨-axis, and, as a result, a single electromagnet placed just below our sample area is utilized for vertical motion. To track the cellís positions in the z-axis, intensity profiles of non-motile cells at varying distances from the focal plane are used. During vertical motion along the z-axis, the intensity difference from the background decreases while the cell size increases. Since the cell is pear-shaped, the eccentricity is high during planar motion, but lowers during vertical motion due to the change in orientation. The three-dimensional control of the live organism T. pyriformis as a cellular robot shows great potential to be utilized for practical applications in microscale tasks, such as target transport and cell therapy.

 

 

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