ICRA 2011 Paper Abstract


Paper WeP207.5

Nakajima, Masahiro (Nagoya University), Hirano, Takanori (Nagoya University), Kojima, Masaru (Nagoya University), Hisamoto, Naoki (Nagoya University), Homma, Michio (Nagoya University), Fukuda, Toshio (Nagoya University)

Direct Nano-Injection Method by Nanoroprobe Insertion Based on E-SEM Nanorobotic Manipulation under Hybrid Microscope

Scheduled for presentation during the Regular Sessions "Micro-Nano Robots and Applications to Life Science" (WeP207), Wednesday, May 11, 2011, 16:25−16:40, Room 5B

2011 IEEE International Conference on Robotics and Automation, May 9-13, 2011, Shanghai International Conference Center, Shanghai, China

This information is tentative and subject to change. Compiled on July 14, 2020

Keywords Micro/Nano Robots, Micro and Nanoscale Automation, Automation in Life Sciences: Biotechnology, Pharmaceutical and Health Care


This paper presents a novel nano-injection method by nanoprobe insertion based on environmental-scanning electron microscope (E-SEM) under hybrid microscope. The hybrid microscope is designed to combine the optical microscope (OM) and E-SEM to realize biological specimen analysis by optical imaging including fluorescent imaging, and nano-scale manipulation by E-SEM imaging. Based on the bio-nano manipulation system, we propose a nano-injection method by nanoprobe insertion. The nanoprobe is designed to have a sharp tip to insert the probe into biological specimen. It is fabricated by focused ion beam (FIB) process. The nano-scale size is important for minimal damage to biological specimen. The Caenorhabditis elegans (C. elegans) is used as a target biological specimen, which is one of the important model organism for diseases analysis. The nanoinjection technique is needed to transport fluorescent materials or specific biological organism into specific cell for in-vivo experiment. The proposed system is considered to be important as future nano-surgery system for life innovation using model organism.



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